MGF IGF-1 Ec 5mg

MGF IGF-1 Ec 5mg

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MGF is a splice variant of insulin-like growth factor-1 (IGF-1Ec), expressed in response to mechanical overload and cellular stress. This research peptide acts via the IGF-1 receptor and PI3K/Akt pathways to regulate myogenic differentiation, proliferation, and repair signaling. It serves as a model compound in studies of mechano-sensitive peptide signaling, muscle regeneration, and anabolic gene expression.

For research use only. Not for human consumption.

References:
Yang SY et al., FEBS Lett, 1996 390(3):289–292
Philippou A et al., Mol Biol Rep, 2007 34(1):37–44
Mills P et al., Growth Horm IGF Res, 2007 17(5):376–385

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InChI InChI=1S/C121H199N41O40/c1-60(166)93(158-108(191)80(55-89(130)173)153-101(184)68(23-8-12-44-123)146-107(190)79(54-88(129)172)155-115(198)95(62(3)168)160-111(194)83(59-165)157-112(195)84-29-18-50-161(84)117(200)85-30-19-51-162(85)116(199)76(36-40-87(128)171)151-96(179)66(126)52-64-31-33-65(169)34-32-64)113(196)150-69(24-9-13-45-124)102(185)156-82(58-164)109(192)149-73(35-39-86(127)170)103(186)144-71(27-16-48-138-120(133)134)99(182)143-70(26-15-47-137-119(131)132)98(181)142-67(22-7-11-43-122)97(180)140-56-90(174)141-81(57-163)110(193)159-94(61(2)167)114(197)154-78(53-63-20-5-4-6-21-63)106(189)148-75(38-42-92(177)178)105(188)147-74(37-41-91(175)176)104(187)145-72(28-17-49-139-121(135)136)100(183)152-77(118(201)202)25-10-14-46-125/h4-6,20-21,31-34,60-62,66-85,93-95,163-169H,7-19,22-30,35-59,122-126H2,1-3H3,(H2,127,170)(H2,128,171)(H2,129,172)(H2,130,173)(H,140,180)(H,141,174)(H,142,181)(H,143,182)(H,144,186)(H,145,187)(H,146,190)(H,147,188)(H,148,189)(H,149,192)(H,150,196)(H,151,179)(H,152,183)(H,153,184)(H,154,197)(H,155,198)(H,156,185)(H,157,195)(H,158,191)(H,159,193)(H,160,194)(H,175,176)(H,177,178)(H,201,202)(H4,131,132,137)(H4,133,134,138)(H4,135,136,139)/t60-,61-,62-,66+,67+,68+,69+,70+,71+,72+,73+,74+,75+,76+,77+,78+,79+,80+,81+,82+,83+,84+,85+,93+,94+,95+/m1/s1

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