Syn-AKE is a research peptide modeled after Waglerin-1, a peptide found in temple viper venom, designed as a tripeptide analog that targets nicotinic acetylcholine receptor (nAChR) subunits in experimental systems. Preclinical studies indicate that Syn-AKE modulates neuromuscular signal transduction and ion channel receptor activity, providing a model for studying peptide–receptor interactions and synaptic transmission. It is utilized in biochemical and dermatological research exploring peptide-based receptor modulation and neurochemical signaling pathways.
For research use only. Not for human consumption.
References:
Nirthanan S et al., Biochim Biophys Acta, 2003 1645(1):81–89
Utkin YN, Toxicon, 2013 71:133–155
Tsetlin V et al., Annu Rev Pharmacol Toxicol, 2015 55:319–341
